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Hyperglycemia may directly cause oxidative stress in all retinal cells or contribute to oxygen deficits in the inner retinal layers due to the retinas high metabolic activity, making it prone to oxidative stress

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Consequently, Vitamin D was proposed as a potentially safer adjuvant treatment option for the management of depressive symptoms.Moreover, while long-term use of SSRIs may result in adverse effects such as decreased bone density [86], Vitamin D has been shown to promote bone health [15]