Possible reasons for this phenomenon include a decline in basal metabolic rate with age, reduced muscle mass leading to decreased energy expenditure, and hormonal changes that affect lipid breakdown and energy utilization [25,26]
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7.5 Natural compounds and microbiota-targeted mitigation strategies The growing interest in natural productsincluding probiotics (e.g., Lactobacillus and Bifidobacterium), prebiotics, and plant-derived compounds such as curcumin and lycopenerepresents a promising direction in food and feed safety
Clinical studies have shown that the level of glutathione, the major antioxidant and redox regulator, is decreased in the cerebrospinal fluid and medial frontal cortex (by 27% and 52% of control level, respectively) of drug naive schizophrenic patients (10) as well as in the post-mortem striatum by (40% of control) (11) and prefrontal cortex of those treated earlier with antipsychotic drugs
Catalytic domain of phosphoinositide-specific phospholipase C (PLC)
