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Oxoproline is a cyclic form of glutamate and is converted into glutamate via oxoprolinase (Figure 5)

This QC sample was plated at different positions on the 96-well plate and injected six times to calculate the coefficient of variation (CV) for data quality control, and undetectable metabolites were excluded from the analysis

But the similarities end there

Growth plate chondrocytes use IGF1R signaling for linear bone growth

The fragment retains the ability to stimulate fat breakdown and inhibit lipogenesis in adipocytes, pathways attributed to interaction with the beta-3 adrenergic receptor in animal models (Heffernan et al., 2001, Journal of Endocrinology)