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FIGURE 3 Nuclear factor-erythroid-derived 2-like 2 (NFE2L2, also named Nrf2) is a transcription factor which plays a crucial role in resistance to oxidative stress (Xu et al., 2021)

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One Adrenal fatigue treatment that we recommend is NAD therapy

However, newer research is painting a clearer picture of the actual risks and benefits

Therefore, any new adjunctive or preventative therapeutics developed will need to be designed around maintaining ROS and antioxidant levels within an acceptable range, which may require longitudinal monitoring of one or more oxidative stress biomarker(s) [146] in patient blood cells