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That question originated in an Australian university laboratory, was carried into a commercial development program with a stabilized analogue, tested in a series of controlled human trials, and ultimately routed away from drug registration and toward a US dietary-ingredient determination
Adequate B vitamin availability supports: Normal digestive enzyme activity Maintenance and repair of the intestinal lining Neural signaling involved in GI motility Effective nutrient absorption This makes B-complex particularly relevant for individuals with altered intake, impaired absorption, or increased gastrointestinal stress
[PubMed: 22131550] 40
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