The reduction was caused by decreased NO signaling, but eNOS expression was unchanged ( 2+ signaling) or downstream of eNOS (i.e., cyclic GMP signaling, nitrosylation of target proteins, etc.)
There is a slight chance, of side effects with collagen supplementation, including: Constipation Diarrhea Reduction of appetite Mild headaches Difficulty sleeping Bloating, heavy feeling, or fullness in the stomach Heartburn Rashes Hypercalcemia (abnormally high calcium levels) Irritability, anxiety, and depression Rarely, collagen supplements can slightly increase the risk of developing kidney stones
Use moisturizer/lotion after
Results for all cognitive tests are presented in Supplementary Table 2
Neuropsychological changes after 30-day Ginkgo biloba administration in healthy participants