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John Buse, who has served as a principal investigator in multiple semaglutide trials, noted: "The glycemic efficacy of semaglutide is remarkably consistent across age subgroups, and we do not titrate differently for a 35-year-old versus a 55-year-old." Glycemic Outcomes: What the SUSTAIN Trials Show The SUSTAIN program comprises multiple phase 3 trials that established semaglutide's efficacy and safety profile

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