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Overexpression of FSP1 or treatment with Fer-1, a ferroptosis inhibitor, significantly reversed the apoptosis, ferroptosis, and lipid peroxidation induced by the activation of the MPO/HOCl signaling pathway, exerting neuroprotective effects

Of these mice, those given a (microbe rich) fecal transplant from Parkinsons patients, rather than healthy people, ended up with more dysbiosis, intestinal problems, and Parkinsonian motor deficits

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and the paracellular route for hydrophilic molecules and ions