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At normal therapeutic doses (up to 3,0004,000 mg/day in adults), hepatic glutathione stores are typically adequate for NAPQI neutralization and rapid regeneration

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doi:10.1016/j.jconrel.2011.01.030

Excessive absorption or an imbalance of iron circulation can easily lead to iron overload, which will contribute to oxidative damage and even cell death due to irons ability to accept and donate electrons ( Most mammalian cells uptake iron (Fe 2+ ) mainly in two ways: intestinal absorption and senescent erythrocyte degradation

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