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Investigators in a recent study hypothesized this mechanism as a potential mode of action for TB-500, noting that inhibiting miR-146a appeared to have reversed the suppression of IRAK1 and TRAF6 by T4, indicative of a likely anti-inflammatory mechanism

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It supports the health of nerve cells and contributes to the normal myelination process

Increasing SLC25A51 expression has been demonstrated to enhance mitochondrial NAD + uptake, thereby maintaining SIRT3 activity and regulating lipid homeostasis through AMPK