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The most common side effect is mild skin irritation at the application site

"Weight loss in itself can then have flow-on effects, particularly on your cardiovascular risk factors like your blood pressure, like your cholesterol and other things," she said

This results in reduced caloric consumption and weight loss (6)

I started to notice immediate effect on my hunger and cravings, and it took about six weeks before I started to really notice a change in how my body looked in the mirror

For patients taking oral semaglutide (Rybelsus), follow the specific administration instructions (taking on an empty stomach with a small amount of water) to ensure proper absorption