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Dona Bibliografa Kasturi, S.S

More consistent movement and training can contribute to fat loss, but the peptide itself is not the mechanism doing the work

When GLP-1 binds to GLP-1R on the surface of -cells, cAMP-dependent PKA is activated and subsequently activates the downstream signal PI3K, which inhibits apoptosis in islet -cells by blocking the expression of the pro-apoptotic protein Bax (Li et al., 2021) (Figure 4)