In the context of gastric cancer, GPNA inhibits Gln uptake by targeting SLC1A5, thereby enhancing the anti-tumor effects of cetuximab both in vivo and in vitro ( 99)
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In addition, experimental studies have shown that the elevation of GSH can inhibit the activation of hepatic stellate cells [33], which is a key driving factor for extracellular matrix deposition and fibrosis, thereby preventing the progression of liver fibrosis [34]
Su H, Ren H, Maimaitikelimu X, Xu J, Bian F, Wang H
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