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In contrast, the buildup of lipid ROS and the consequent onset of ferroptosis can be hindered through intervention with iron-chelating agents (e.g., deferoxamine) and lipophilic antioxidants (e.g., ferrostatin-1 and liproxstatin-1) [77]

A 2023 review in Obesity noted that dual-therapy users reported higher rates of these adverse events compared to monotherapy groups

However, whilst there is no official contraindication to taking these medications together, it is important to consider the practical implications

Weng Y, Zhang S, Huang W, Xie X, Ma Z, Fan Q

Investigated for its role in energy expenditure and diet-induced fat accumulation