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Given that NACA was able to counteract the effects of the ACOX1 gain-of-function mutation, antioxidant treatment was considered for patient#1 during a severe disease flare

1,11,19 Novel pharmacological agents, including sodium-glucose cotransporter 2 (SGLT2) inhibitors, glucagon-like peptide-1 (GLP-1) receptor agonists, and ion channel blockers, have shown promising neuroprotective and pain management effects

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Started BPC/TB-500 and within three weeks the improvement was significant