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A deep understanding of the weight regulation mechanism and the impact of the gut-brain axis on appetite has spurred the development of incretin-based medications, such as GLP-1 receptor agonists

We found no interactions, except between prior suicide attempts and sex in the comparison of GLP-1 RAs and SGLT-2 inhibitors, indicating that the effect of prior suicide attempts on the risk of a subsequent suicide attempt is greater among men

Tailoring treatment to each persons needs is essential for the best results