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TGR5 is the target of different BAs, but the most potent endogenous agonist has shown to be lithocholic acid (LCA) and its taurine conjugates with activity at nanomolar concentrations (273, 339)

TEM 9 , 124128 (1998)

For the vast majority of people*, short-acting ADHD medications (such as dexamphetamine and Ritalin) are much harder to get right because symptom management is likely to vary throughout the day

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