4: Sikiric P, Barisic I, Udovicic M, Lovric Bencic M, Balenovic D, Strinic D, Zivanovic Posilovic G, Uzun S, Vranes H, Krezic I, Lozic M, Stambolija V, Premuzic Mestrovic I, Beketic Oreskovic L, Oreskovic I, Strbe S, Sikiric S, Tomic L, Kordic M, Tvrdeic A, Seiwerth S, Boban Blagaic A, Skrtic A
These changes shift energy metabolism from glycolysis toward OXPHOS, increase ATP levels and mitochondrial ROS, and activate p53 via ATR-dependent stress signaling
some of these variants overlap with Mendelian disease genes
Once-weekly dosing is preferred by 68% of patients, improving adherence rates by 32% compared to daily injections
The analysis is performed on ejaculate samples elicited on two occasions separated by at least one week and each following at least three days of abstinence