glp 1 triglycerides Distinct and complementary metabolic effects of GLP-1 and glucagon receptor agonism in diet-induced obese mice Peptide‐based multi‐agonists: a new paradigm

glp 1 triglycerides

glp 1 triglycerides Distinct and complementary metabolic effects of GLP-1 and glucagon receptor agonism in diet-induced obese mice Peptide‐based multi‐agonists: a new paradigm

Name: glp 1 triglycerides Distinct and complementary metabolic effects of GLP-1 and glucagon receptor agonism in diet-induced obese mice Peptide‐based multi‐agonists: a new paradigm
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doi: 10.1016/j.lfs.2018.10.063 7 FanYPedersenO

Why Is It So Hyped

Here we present the oxygen-to-sulfur exchange strategy, that transforms traditional carboxamides to thioamides, yielding electrophilic warheads, including chlorothioacetamides and fluorothioacetamides, with enhanced cysteine reactivity, while retaining aqueous stability and selectivity