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^Procter & Gamble calculation based in part on data reported by NielsenIQ through its ScanTrack Service for the Fiber Supplements (branded only) for the 52-weeks period ending 04/09/22, for the Total U.S

Figure 2 Importantly, in the SELECT trial, differences in rates of cardiovascular events between semaglutide and placebo began to emerge within the first few months suggesting that weight loss alone may not account for the full benefits ( On the co-morbidities front, GLP-1R is not expressed in the liver and the data generated with semaglutide in NASH patients seems to support a lack of a direct antifibrotic effect (152)

Presented at NAVDF April 10-13, 2019, Austin, TX.

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Camini FC, da Silva Caetano CC, Almeida LT, de Brito Magalhes CL