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The same publication also detected an increased abundance of the genus Colidextribacter in patients with impaired intestinal permeability [38]: this taxon has previously been described to play a role in the increase of cellular oxidative stress capacity in a mice model, thus contributing to gut barrier impairment [38]

Study Objective and Why This Research Matters The central objective of this study was to determine whether supplementing older male rats with a combined daily dose of vitamin C and GSH could reduce age-associated oxidative stress and modulate downstream biochemical changes