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The library comprised 10,480 electrophilic compounds with diverse warheads that target cysteines (for example, acrylamides and chloroacetamides) or other nucleophilic residues (for example, aldehydes and boronic acids) (Extended Data Fig

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However, natural glutathione synthesis in these cells relies on the recycling of its constituents, and as a consequence, the increase in glutathione circulating in the blood can still support this process

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