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In an interventional study, it was shown that L-carnitine supplementation with a dose of 3 g/day for 12 weeks significantly reduced FBG, but its effects on HbA1c reduction were not significant in diabetic patients ( Subgroup analysis of our findings showed that trial duration, intervention dose, and BMI status significantly affect the insulin level, as well as, it was shown that trial duration, intervention dose, obesity, and health status have a significant effect on the HOMA-IR levels

Finally, this study evaluated pulmonary toxicity exclusively in male rats to minimize hormonal variability