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Chronic cisplatin ototoxicity paradigm: Under anesthesia, animals are administered once every 4-days regimen intraperitoneal injections of cisplatin (3-5 mg/kg) over a 30-min period, for a total of up to 6 injections

This peptide is generally considered safe for clinical use, with most subjects not experiencing adverse effects

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As metabolic regulation of fibroblasts and keratinocytes during re-epithelialisation is known to be important 127 , future studies should aim to further investigate the role of the MAPK and other relevant signalling pathways

Muellers approach to medicine is refreshing