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Novo Nordisk has responded by planning a higher-dose CagriSema trial (REDEFINE 11), expected to report in early 2027, and by filing an NDA at the current dose

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It includes evaluating the patients medical background, skin type, and any possible allergies or underlying diseases that can compromise the procedures safety

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Indeed, numerous studies have revealed significant cellular changes in age-associated delayed healing: altered haemostasis [138, 139], reduced re-epithelialisation [140, 141], an excessive inflammatory response [142, 143] and upregulated protease activity associated with reduced matrix deposition [144]