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Additionally, efforts to enhance intrinsic neuronal protective mechanisms, through upregulation of neurotrophic factors, restoration of calcium homeostasis, or stabilization of synaptic plasticity, offer further promise [29, 30]

The US Congressional Budget Office (CBO) and independent researchers have analysed the cost of allowing Medicare to cover anti-obesity medications, including GLP-1s

Goodman & Gilmans The Pharmacological Basis of Therapeutics

Acknowledgments We express our gratitude to BioRender (www.BioRender.com) for their graphical assistance during the preparation of this manuscript

Follow your healthcare provider's instructions on dosage and timing