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10,11 IMPORTANT INFORMATION ABOUT COMPOUNDED MEDICATIONS This medication has been compounded (custom-prepared) by a pharmacy

Under stressful circumstances, Lactobacillus casei strain Shirota (LcS) may prevent cortisol hypersecretion and physical symptoms, possibly through reducing stress reactivity in the paraventricular nucleus (PVN) and vagal afferent signaling to the brain (195)

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OVX mice are widely used to model a range of human age-associated pathologies, including osteoporosis, neurodegeneration and cardiac dysfunction, as well as perimenopausal symptoms, such as depression and hot flushes [110112]

doi:10.1016/j.bpc.2016.12.004 Ratan ZA, Haidere MF, Hong YH, et al