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GHK-Cu may prevent oxidative stress in skin by regulating copper and modifying expression of numerous antioxidant genes

2) failed to detect any significant differences in GLR1 and GSH1 expression

Liraglutide, the active comparator, was initiated at 0.6 mg daily and titrated weekly up to 3.0 mg

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Histone modifiers are also dysregulated: histone deacetylases (HDAC1-3, SIRT1), methyltransferases (EZH2, MLL1), and demethylases (LSD1) alter chromatin states, contributing to progesterone resistance, inflammation, and fibrosis