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Calocurb's data represents apples-to-apples comparison because they're measuring actual hormone levels and appetite effects in similar populations, unlike typical comparisons where ingredients like berberine might increase GLP-1 by 65% -- enough for blood glucose management or statistical significance but not appetite suppression or clinical significance

Indeed, a small study by Gao et al (2019), involving 6 human participants, reported that a lowered dietary methionine intake may lead to a significant reduction of circulating homocysteine along with reductions in L- cysteine, N- acetyl cysteine, glutathione and a significant increase in circulating riboflavin (vitamin B 2 ) after 3 weeks

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