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This condition affects the viability of ATP, which is compartmentalized into cytosolic and membrane-bound pools in RBCs (7, 11, 50)

Initially known by forming glial scar after the initial inflammatory insult, many other functions are now identified for astrocytes in MS such as recruiting leukocytes for CNS, microglia activation, boosting neurodegeneration, as well as contributing for neuroprotection and limiting the area of inflammation (97)

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It is one of the most metabolically active tissues in the body, which means it produces a lot of free radicals

*Correspondence: Jia Zhao, [email protected] Rong, [email protected] This article was submitted to Anxiety and Stress Disorders, a section of the journal Frontiers in Psychiatry Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers