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No fluid retention or edema Growth hormone commonly causes water retention, leading to bloating, swelling in extremities, and a puffy appearance

Figure 4 Indeed, requiring FAD as coenzyme, methylenetetrahydrofolate reductase (MTHFR) is responsible for the formation of 5-methyltetrahydrofolate

But one question comes up more than any other: "Will I have to be on TRT for the rest of my lif