Through experimental methods such as molecular docking, CESTA, and non-targeted metabolomics, we found that SAC can act on the Keap1/Nrf2/GPX4 signaling axis and regulate glutathione metabolism, effectively inhibiting ferroptosis and oxidative damage in colonic epithelial cells, thereby alleviating UC
Clinical Implications of ALA ALA has been used in clinical practice for 70 years to alleviate symptoms associated with various diseases, including neurodegenerative disorders, diabetes, cancer, age-related cardiovascular issues, neuromuscular conditions, weight gain caused by antipsychotic medications, and metabolic obesity [1,8,15]
Shruti VC, Prez-Guevara F, Elizalde-Martnez I, Kutralam-Muniasamy G (2020) Reusable masks for COVID-19: A missing piece of the microplastic problem during the global health crisis
From the ASV table (Supplementary Table S1), sums of ASVs within each respective phylum or genus for each sample were calculated to establish the abundance of each phylum or genus per sample
Factors like species, strain, age, weight, and general health are all crucial