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5613 without) were included in the analysis

Occurrence of nausea, vomiting and diarrhoea reported as adverse events in clinical trials studying glucagon-like peptide-1 receptor agonists: A systematic analysis of published clinical trials

The side effects of GLP-1 RAs can include gastrointestinal symptoms such as nausea, vomiting, and diarrhea, which are usually transient but may affect patient adherence, as well as rarer complications that require careful monitoring in clinical practice

Thus, among participants without a current diagnosis of MDD we excluded those with a diagnosis of anxiety disorder (n = 508) and dysthymia or minor depression (n = 66)

What do they mean by chronic supplementation