10.33549/physiolres.934546 192 SirotkinA
The metagenomics analysis (16S rRNA sequencing) of microbial consortia revealed Firmicutes (Bacillota), Actinobacteria (Actinomycetota), Proteobacteria, Bacteroidetes, and Thermotogae as the dominant phyla and GC-MS analysis confirmed the presence of significant metabolites (endpoint of the bioassay) in the biodegradation of ibuprofen, i.e., 2-hydroxy ibuprofen, 1,4-hydroquinone, and 2-hydroxy-1,4-quinol
Histamine and sulfur sensitivity appear to be closely linked, but in some cases, excess sulfur and sulfur metabolism impairment may lead to histamine sensitivity
typically, multiple sessions are recommended for optimal results
In this context, SHMT1 knockdown leads to impaired migratory ability, due to increased ROS levels, reduced ATP generation, and AMPK activation, affecting cytoskeleton remodeling [118]