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Nuclear factor B, for example, becomes more transcriptionally active in response to the contribution of ROS to the degradation of IB, the inhibitory partner of nuclear factor B that sequesters it in the cytosol (Hayden and Ghosh, 2004)

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LRP5/6 deletion promotes cardiac ischaemia, while its downstream target, -catenin, is beneficial in ischaemic injury

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In contrast, the gut contains a dense microbial population, particularly concentrated in the ileum and colon, comprising bacteria such as Streptococcus , lactic acid bacteria, and yeasts