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After an initial loading dose, maintenance doses are typically given every 2-3 months

65 However, as this was an open-label, uncontrolled trial, it is impossible to assess how much of the improvement was due to a placebo effect

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Lack of sleep can interfere with these processes and lead to weight gain, mood swings, and decreased cognitive function

Only eCATH-2 and eCATH-3 were detected, being consistent with the observations of the first study