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It is the worlds second-best selling prescription medicine, with combined sales of $26bn in 2024 and growing annually at a staggering 40%
Chicago Dutta, Sanchari Sinha Dutta
When you remove that dual stimulation during a switch, the transition period requires careful dose management to prevent rebound effects
Glycemic markers respond reliably to therapy, with semaglutide tested across 300 clinical trials and 90% showing improved glucose regulation, so falling fasting glucose and HbA1c usually indicate therapeutic effect rather than assay interference
1 Model based estimates based on an analysis of covariance model including treatment and type 2 diabetes status as factors and baseline value as a covariate
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