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When adverse effects occurred, they were typically mild and transient, with the most common being mild to moderate headaches (similar frequency to placebo groups), minor injection site reactions (redness, slight swelling), and gastrointestinal effects at higher oral doses (nausea, diarrhea)

doi: 10.1006/nbdi.2001.0468 53 McDonoughJ

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This single meta-analysis represents the majority of the data seen in this umbrella review , with additional data for inositol, vitamin D and NAC coming from the other three meta-analyses