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This genotype is generally associated with typical or slightly lower endogenous IGF-1 production, which may result in a more modest anabolic response to growth-factor signaling

Clin Pharmacokinet 51:553572 Ricciolini R, Scalibastri M, Kelleher JK, Carminati P, Calvani M, Arduini A (1998) Role of acetyl-l-carnitine in rat brain lipogenesis: implications for polyunsaturated fatty acid biosynthesis

But do not panic, these are concerns under investigation

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