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251 Impaired neurotrophic support In DPN, levels of neurotrophic factors are significantly reduced due to hyperglycemia-induced metabolic disturbances

Gonzlez-Arancibia et al., 2019)

Overall discontinuation rates were higher in the active treatment group versus placebo, in part due to some participants withdrawing over perceived excessive weight loss

Scooty Nickerson can be reached at [email protected].

However, gastrointestinal side effects, including diarrhea, constipation, and abdominal discomfort, have been reported in approximately 35% of patients, especially during initial usage