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3.4 Lipid metabolism In addition to reprogramming glucose and glutamine metabolism, hypoxia significantly influences lipid metabolic pathways in cancer cells (108, 109)

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At concentrations lower than those of DON, JHU395 has been found to decrease the growth and increase the apoptosis of high-MYC medulloblastoma cell lines, thereby prolonging the survival of treated animals (100)

GLP-1 Activation : Tirzepatide activates the GLP-1 receptors, which curb gastric emptying, aiding in prolonged satiety, and also stimulate insulin secretion when blood sugar levels rise

Species-specific metabolic reprogramming in human and mouse microglia during 2 inflammatory pathway induction