Weight can tick up 1-3 pounds from water and glycogen rebound, which is psychologically difficult for some patients
Many semaglutide users need PPIs only during dose titration phases, then successfully step down to H2 blockers or lifestyle management alone once their body adjusts
Along with the GLP-1 pathway, it activates the GIP receptor (which plays a role in insulin secretion and fat storage) and the Glucagon receptor (which promotes fat breakdown and increases energy use)
So when the drugs are then taken away, you havent got those sort of behavioural strategies in place that help keep the weight off. Responding to the findings, Tam Fry, the chair of the National Obesity Forum, said: It shouldnt surprise anyone if people regain weight having used GLP-1 drugs without seriously attempting to improve their lifestyle Using GLP-1 is not the quick fix which many users believe it to be. Jane Ogden, a professor of health psychology at Surrey University, said there was no point just throwing people back out into the world of their own lives, carrying on their own behaviours from before after coming off the injections
11 People with a medical history of pancreatitis, thyroid tumors, diabetic rethinopathies, allergic reactions, and/or kidneys problems need to consult with their physicians before taking any of these medications
