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The pathological state of glial cells regulates the bloodbrain barrier (De Bock et al., 2017) and therefore these cells can be thought of as guardians that protect neurons against oxidative stress (Liu et al., 2018) via the Saposin C/GPR37L1/GPR37 pathway

There is no evidence that this skincare superhero counteracts or impedes any of the activity of other brightening ingredients (think vitamin C, liquorice, arbutin or azelaic acid)

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For GLP1/GIP medication versus lower dose, NNT = 9

At present, the most defensible conclusion is implementation-oriented rather than economic: access, reimbursement, equity, and opportunity cost are likely to shape uptake more strongly than efficacy alone (204, 205)