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Despite the fact there's no evidence and real potential harm

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Low estradiol values may be found in obese women with ovulatory dysfunction and in women during the peri-menopausal and post-menopausal periods

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Chang and colleagues (J Appl Physiol, 2011) documented enhanced tenocyte outgrowth, survival, and migration in cultured Achilles tendon preparations

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10.1038/nchembio.2239 26 DolmaS.LessnickS

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