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Co-existence of furin with ACE2/RAAS in the female and male reproductive systems pose a potential risk on human fertility in COVID-19 patients

Since the use of Dapsone is limited to a small number of transplant patients and since it is often co-administered with other medications that cause anemia, it is prudent to check for concurrent G6PD deficiency before starting Dapsone

Genistein, a soy isoflavone that preferentially binds to ER, has been shown to reduce hypoxia-induced hydrogen peroxide (H 2 O 2 ) production, increase Bcl-2 expression, decrease cytochrome c release from mitochondria, and significantly lower apoptosis rates associated with hypoxia (69)