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In rats fed a high-fat-diet, metformin (200 mg/kg) was shown to reduce glucose absorption by inhibiting the expression of sodium glucose cotransporter-1 in the upper small intestine [36]

Prioritize easily digestible options like oatmeal, berries, cooked vegetables, lentils, and chia seeds

Even if you continue lifestyle interventions and youre eating healthy and exercising, you can still regain at least 3% or 4% of your body weight. Over the course of your treatment, your healthcare provider will gradually increase how much semaglutide youll take until youve reached your desired weight or hit the maximum allowable dose

Yet, the body's response can vary widely

The dose escalation design tested different starting doses (2 mg vs 4 mg) to evaluate tolerability