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Signal Transduct Target Ther 7(1):391 Guo Z, Wang M, Ying X, Yuan J, Wang C, Zhang W, Tian S, Yan X (2023a) Caloric restriction increases the resistance of aged heart to myocardial ischemia/reperfusion injury via modulating AMPKSIRT1PGC1a energy metabolism pathway

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Common Side Effects: Nausea and Vomiting : Frequently occurs when starting semaglutide or increasing the dose Diarrhea: Common during the initial phase of treatment Constipation : Affects some patients during treatment Abdominal Pain : This may occur, often mild to moderate Headache : This can occur, especially at the start of treatment Fatigue : Ensure sufficient rest and a balanced diet