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This figure illustrates the effects of GLP-1 receptor agonists (GLP-1 RAs) and SGLT2 inhibitors on composite cardiovascular outcomes, including all-cause mortality, progression to systolic heart failure, acute myocardial infarction, and stroke, after propensity score matching

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Using sequence alignment between c-Jun, Trib1 and other known substrates, we generated a prediction model for c-Jun binding to COP1 (Fig