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Limited published data exists on this combination, and safety protocols require careful monitoring of blood pressure and neurological symptoms

Acknowledgements Funding This review and the article processing charges were funded by Eli Lilly Australia

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Thus, the inherent reactivity of low molecular weight thiol compounds depends on the acid dissociation constant (pKa) of their thiol groups, i.e., the lower the pKa the higher the reactivity of the thiol (Wall et al., 2012)