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For example, MSCs secrete hepatocyte growth factor and upregulate c-Met expression to reduce hepatic ischemia-reperfusion injury [54] or regulate other signaling pathways, such as increasing NRF2 to reduce acute liver injury [55]

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In another study of 147 patients with painful DPN and an average daily pain (ADP) score 4, the ADP score decreased more in patients treated with gabapentin extended-release formula than in those treated with placebo (gabapentin, 2.76

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